Korean scientists have discovered a new molecular compound that could increase the efficiency of human adult cell reprogramming to induced pluripotent stem cells. The low-molecule Reprogramming Stimulating Compound 133, or RSC133, adds to the list of non-viral vectors that are crucial to advancing the biotechnology and production of iPS cells.
Dr. Cho Yee-sook and Dr. Lee Jung-woon of the Korea Research Institute of Bioscience & Biotechnology led a team of researchers for this latest discovery that was published in Angewandte Chemie International journal early this month.
It said that the compound derivative acts as the “booster of pluripotency,” and it “potently improves the reprogramming of human somatic cells into a pluripotent state and aids the growth and maintenance of human pluripotent stem cells.” Pluripotent stem cells, like embryonic stem cells, can be turned into any type of cell in the body.
For full article, see Korea Herald.